Marc Peters-Golden Selected Research

Arachidonate 5-Lipoxygenase (5 Lipoxygenase)

1/2020	A new treatment for severe pulmonary arterial hypertension based on an old idea: inhibition of 5-lipoxygenase.
10/2017	Leukotriene B4 antagonism ameliorates experimental lymphedema.
1/2014	Pivotal role of the 5-lipoxygenase pathway in lung injury after experimental sepsis.
7/2010	Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferator-activated receptor-alpha agonist.
5/2010	Intrapulmonary administration of leukotriene B4 enhances pulmonary host defense against pneumococcal pneumonia.
1/2009	Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.
2/2005	Opposing and hierarchical roles of leukotrienes in local innate immune versus vascular responses in a model of sepsis.
10/2004	Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages.
1/2002	Protection from pulmonary fibrosis in leukotriene-deficient mice.

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Marc Peters-Golden Research Topics

Disease

25	Inflammation (Inflammations) 01/2020 - 04/2002
19	Infections 01/2018 - 09/2006
16	Asthma (Bronchial Asthma) 01/2020 - 09/2002
14	Fibrosis (Cirrhosis) 01/2022 - 01/2003
13	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 01/2002
8	Pneumonia (Pneumonitis) 10/2014 - 04/2002
6	Lung Diseases (Lung Disease) 03/2022 - 06/2005
6	Pneumococcal Pneumonia 01/2018 - 01/2006
6	Idiopathic Pulmonary Fibrosis 06/2014 - 08/2005
5	Bacterial Pneumonia 01/2016 - 04/2002
5	Sepsis (Septicemia) 01/2014 - 10/2004
4	Pulmonary Arterial Hypertension 01/2020 - 08/2013
4	Lung Injury 11/2017 - 05/2005
4	Bacterial Infections (Bacterial Infection) 01/2016 - 08/2009
3	Pulmonary Hypertension 01/2020 - 08/2013
3	Cicatrix (Scar) 11/2019 - 09/2011
3	Neoplasms (Cancer) 10/2019 - 08/2012
3	Starvation 01/2018 - 04/2002
3	Acute Lung Injury 10/2012 - 08/2005
3	Pneumococcal Infections 05/2012 - 08/2009
3	Airway Remodeling 11/2011 - 01/2003
2	Obesity 01/2018 - 10/2008
2	Fever (Fevers) 01/2017 - 06/2005
2	Colitis 12/2014 - 01/2013
2	Endometritis 09/2013 - 06/2008
2	Tuberculosis (Tuberculoses) 12/2012 - 04/2007
2	Peritonitis 03/2012 - 02/2005
2	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2009 - 01/2008
2	Malnutrition (Nutritional Deficiencies) 01/2005 - 04/2002
1	Hypoxia (Hypoxemia) 10/2019
1	Lung Neoplasms (Lung Cancer) 10/2019
1	Adenocarcinoma of Lung 10/2019
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018
1	Bronchial Spasm 01/2018
1	Edema (Dropsy) 10/2017
1	Lymphedema (Milroy Disease) 10/2017
1	Septic Shock (Toxic Shock Syndrome) 01/2017
1	Disease Progression 01/2016

Drug/Important Bio-Agent (IBA)

23	LeukotrienesIBA 12/2014 - 01/2002
20	LipidsIBA 01/2016 - 09/2002
19	Dinoprostone (PGE2)FDA Link 03/2022 - 01/2008
14	ProstaglandinsIBA 01/2016 - 04/2002
13	Prostaglandins EIBA 12/2012 - 06/2003
11	CytokinesIBA 01/2020 - 01/2003
9	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2020 - 01/2002
9	Leukotriene B4IBA 10/2017 - 09/2006
8	CollagenIBA 01/2021 - 01/2003
7	Bleomycin (Blenoxane)FDA LinkGeneric 01/2018 - 01/2002
6	LeptinIBA 01/2018 - 04/2002
5	cysteinyl-leukotrieneIBA 01/2011 - 01/2003
5	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 07/2008 - 01/2003
5	EicosanoidsIBA 06/2008 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 01/2016 - 10/2008
3	Hormones (Hormone)IBA 01/2018 - 01/2006
3	AllergensIBA 02/2017 - 06/2005
3	EnzymesIBA 01/2016 - 01/2009
2	InterleukinsIBA 01/2020 - 01/2020
2	Interleukin-13IBA 01/2020 - 01/2018
2	Liposomes (Liposome)IBA 01/2020 - 10/2019
2	MonocrotalineIBA 10/2019 - 08/2013
2	Leptin ReceptorsIBA 01/2018 - 07/2012
2	Ketoprofen (Orudis)FDA LinkGeneric 10/2017 - 12/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2015 - 06/2011
2	Misoprostol (Cytotec)FDA LinkGeneric 02/2014 - 06/2008
2	Interleukin-6 (Interleukin 6)IBA 01/2014 - 09/2013
2	montelukast (Singulair)FDA Link 01/2014 - 06/2005
2	Interleukin-17 (Interleukin 17)IBA 01/2014 - 09/2013
2	Biological ProductsIBA 09/2013 - 11/2011
2	Messenger RNA (mRNA)IBA 12/2012 - 01/2008
2	AntigensIBA 12/2012 - 11/2011
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2012 - 07/2004
2	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2012 - 12/2007
2	Arachidonic Acid (Vitamin F)IBA 05/2010 - 09/2002
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 07/2008 - 06/2003
2	Fluorescein-5-isothiocyanate (FITC)IBA 12/2007 - 05/2005
1	Epoprostenol ReceptorsIBA 03/2022
1	Bortezomib (Velcade)FDA Link 01/2022
1	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022
1	Lipoxygenase InhibitorsIBA 01/2020
1	Inflammation MediatorsIBA 01/2020
1	Leukotriene Receptors (Leukotriene Receptor)IBA 01/2020
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2020
1	Extracellular Matrix ProteinsIBA 11/2019
1	Semaxinib (SU5416)IBA 10/2019
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 10/2019
1	AutacoidsIBA 01/2018
1	siomycin AIBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 10/2017
1	Pharmaceutical PreparationsIBA 10/2017
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 10/2017
1	DecorinIBA 01/2016
1	Hydroxyproline (4 Hydroxyproline)IBA 01/2016
1	Prostaglandin-E SynthasesIBA 01/2016
1	Suppressor of Cytokine Signaling 3 ProteinIBA 01/2016
1	Collagen Type I (Type I Collagen)IBA 01/2016
1	AnaphylatoxinsIBA 01/2016

Therapy/Procedure

8	Therapeutics 01/2022 - 01/2003
7	Ligation 01/2014 - 07/2004
3	Punctures 01/2014 - 02/2005